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KMID : 0388720110180040268
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Journal of Korean Society of Spine Surgery
2011 Volume.18 No. 4 p.268 ~ p.272
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Gelfoam Granuloma Formation and Myelopathy after Posterior Decompression in Thoracic Spine - A Case Report -
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Lee Kyu-Yeol
Kang Jin-Hun
Kim Hyo-Jong
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Abstract
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Study Design: A case report.
Objectives: To document that Gelfoam® (Pharmacia & Upjohn, Kalamazoo, MI) contributes to granuloma formation and spinal cord irritation by immune response.
Summary of Literature Review: The Gelfoam® or microfibrillar collagen applied during various operation for hemostasis. Some complications of Gelfoam®, such as mechanical cord compression, postoperative swelling and mass effect in closed cavity have been reported.
Materials and Methods: The patient was underwent posterior decompression and instrumented posterolateral fusion under the diagnosis of the ossification of ligamentum flavum at T10-11 and T11-12. In operation, Gelfoam® was used at epidural space. She complained of sensory deterioration and muscle weakness around lower extremities after 10days postoperatively. A second operation was performed.
Results: Postoperatively, the patient immediately improved motor grade except spasticity. She is under observation.
Conclusions: Gelfoam® at epidural space after posterior decompression can result hyperactive immune reaction and irritate spinal cord.
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KEYWORD
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Gelfoam®, Immune reaction, Spinal fusion
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